| 2020-09-12 11:00:00September 12, 2020 | Stoke City vs Burnley | 1 - 3 | U18 Premier League North | Clayton Wood | Recap | 1 |
| 2020-09-12 11:00:11September 12, 2020 | West Ham United vs Tottenham Hotspur | 1 - 4 | U18 Premier League South | | Recap | 1 |
| 2020-09-12 11:00:15September 12, 2020 | Aston Villa vs Leicester City | 2 - 1 | U18 Premier League South | Bodymoor Heath Training Ground | Recap | 1 |
| 2020-09-12 11:00:39September 12, 2020 | Everton vs Blackburn Rovers | 2 - 1 | U18 Premier League North | Finch Farm | Recap | 1 |
| 2020-09-12 11:00:46September 12, 2020 | Leeds United vs Middlesbrough | 0 - 3 | U18 Premier League North | Thorp Arch | Recap | 1 |
| 2020-09-12 11:00:53September 12, 2020 | Brighton and Hove Albion vs Chelsea | 1 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | Recap | 1 |
| 2020-09-12 11:30:04September 12, 2020 | Arsenal vs Southampton | 4 - 2 | U18 Premier League South | Shenley Training Centre | Recap | 1 |
| 2020-09-12 12:00:45September 12, 2020 | Norwich City vs West Bromwich Albion | 5 - 1 | U18 Premier League South | Colney Training Centre | Recap | 1 |
| 2020-09-12 13:00:55September 12, 2020 | Derby County vs Sunderland | 2 - 0 | U18 Premier League North | Derby County Football Academy | Recap | 1 |
| 2020-09-12 14:00:08September 12, 2020 | Manchester City vs Wolverhampton Wanderers | 4 - 1 | U18 Premier League North | Academy Stadium | Recap | 1 |
| 2020-09-18 11:00:40September 18, 2020 | Brighton and Hove Albion vs Fulham | 1 - 3 | U18 Premier League South | The Amex Elite Football Performance Centre | Recap | 2 |
| 2020-09-19 10:30:08September 19, 2020 | Chelsea vs West Ham United | 4 - 1 | U18 Premier League South | Cobham Training Centre | Recap | 2 |
| 2020-09-19 11:00:21September 19, 2020 | Tottenham Hotspur vs Arsenal | 2 - 0 | U18 Premier League South | | Recap | 2 |
| 2020-09-19 11:00:22September 19, 2020 | Southampton vs Crystal Palace | 1 - 2 | U18 Premier League South | Staplewood Training Ground | Recap | 2 |
| 2020-09-19 11:00:31September 19, 2020 | Manchester United vs Blackburn Rovers | 2 - 1 | U18 Premier League North | Aon Training Complex | Recap | 2 |
| 2020-09-19 11:00:41September 19, 2020 | Liverpool vs Stoke City | 5 - 0 | U18 Premier League North | Liverpool Academy | Recap | 2 |
| 2020-09-19 12:00:51September 19, 2020 | Burnley vs Wolverhampton Wanderers | 1 - 2 | U18 Premier League North | Leyland County Ground | Recap | 2 |
| 2020-09-19 12:00:55September 19, 2020 | West Bromwich Albion vs Reading | 3 - 3 | U18 Premier League South | | Recap | 2 |
| 2020-09-19 12:30:44September 19, 2020 | Middlesbrough vs Derby County | 2 - 3 | U18 Premier League North | Rockliffe Park | Recap | 2 |
| 2020-09-19 13:00:48September 19, 2020 | Norwich City vs Aston Villa | 0 - 1 | U18 Premier League South | Colney Training Centre | Recap | 2 |
| 2020-09-19 14:00:43September 19, 2020 | Newcastle United vs Leeds United | 2 - 2 | U18 Premier League North | Newcastle United Academy | Recap | 2 |
| 2020-09-19 14:00:50September 19, 2020 | Manchester City vs Everton | 2 - 2 | U18 Premier League North | Academy Stadium | Recap | 2 |
| 2020-09-26 11:00:10September 26, 2020 | Chelsea vs Southampton | 1 - 1 | U18 Premier League South | Cobham Training Centre | Recap | 3 |
| 2020-09-26 11:00:14September 26, 2020 | West Ham United vs Fulham | 1 - 2 | U18 Premier League South | | Recap | 3 |
| 2020-09-26 11:00:20September 26, 2020 | Manchester United vs Burnley | 5 - 1 | U18 Premier League North | Aon Training Complex | Recap | 3 |
| 2020-09-26 11:00:21September 26, 2020 | Liverpool vs Manchester City | 1 - 3 | U18 Premier League North | Liverpool Academy | Recap | 3 |
| 2020-09-26 11:00:25September 26, 2020 | Arsenal vs Crystal Palace | 3 - 2 | U18 Premier League South | Shenley Training Centre | Recap | 3 |
| 2020-09-26 11:00:36September 26, 2020 | Middlesbrough vs Sunderland | 4 - 0 | U18 Premier League North | Rockliffe Park | Recap | 3 |
| 2020-09-26 11:00:46September 26, 2020 | Everton vs Stoke City | 4 - 0 | U18 Premier League North | Finch Farm | Recap | 3 |
| 2020-09-26 11:30:02September 26, 2020 | Brighton and Hove Albion vs Tottenham Hotspur | 1 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | Recap | 3 |
| 2020-09-26 12:00:23September 26, 2020 | Norwich City vs Leicester City | 4 - 2 | U18 Premier League South | Colney Training Centre | Recap | 3 |
| 2020-09-26 12:00:33September 26, 2020 | Aston Villa vs Reading | 3 - 1 | U18 Premier League South | Bodymoor Heath Training Ground | Recap | 3 |
| 2020-09-26 12:00:35September 26, 2020 | Blackburn Rovers vs Wolverhampton Wanderers | 2 - 3 | U18 Premier League North | Brockhall | Recap | 3 |
| 2020-09-26 13:00:01September 26, 2020 | Derby County vs Newcastle United | 4 - 3 | U18 Premier League North | Derby County Football Academy | Recap | 3 |
| 2020-10-02 14:00:17October 2, 2020 | Chelsea vs Crystal Palace | 0 - 1 | U18 Premier League South | Cobham Training Centre | Recap | 4 |
| 2020-10-03 11:00:03October 3, 2020 | Burnley vs Everton | 2 - 3 | U18 Premier League North | Leyland County Ground | Recap | 4 |
| 2020-10-03 11:00:04October 3, 2020 | Stoke City vs Wolverhampton Wanderers | 2 - 0 | U18 Premier League North | Clayton Wood | Recap | 4 |
| 2020-10-03 11:00:05October 3, 2020 | Southampton vs Brighton and Hove Albion | 0 - 2 | U18 Premier League South | Staplewood Training Ground | Recap | 4 |
| 2020-10-03 11:00:12October 3, 2020 | Blackburn Rovers vs Liverpool | 0 - 3 | U18 Premier League North | Brockhall | Recap | 4 |
| 2020-10-03 11:00:19October 3, 2020 | Tottenham Hotspur vs Fulham | 3 - 0 | U18 Premier League South | Tottenham Hotspur Training Centre | Recap | 4 |
| 2020-10-03 11:00:42October 3, 2020 | West Bromwich Albion vs Aston Villa | 1 - 2 | U18 Premier League South | | Recap | 4 |
| 2020-10-03 11:00:49October 3, 2020 | Newcastle United vs Middlesbrough | 3 - 4 | U18 Premier League North | Newcastle United Academy | Recap | 4 |
| 2020-10-03 11:00:55October 3, 2020 | West Ham United vs Arsenal | 3 - 2 | U18 Premier League South | | Recap | 4 |
| 2020-10-03 11:30:53October 3, 2020 | Sunderland vs Leeds United | 1 - 3 | U18 Premier League North | Eppleton Colliery Welfare Ground | Recap | 4 |
| 2020-10-03 12:00:00October 3, 2020 | Reading vs Leicester City | 3 - 2 | U18 Premier League South | Reading Training Ground | Recap | 4 |
| 2020-10-03 14:00:13October 3, 2020 | Manchester City vs Manchester United | 2 - 1 | U18 Premier League North | Academy Stadium | Recap | 4 |
| 2020-10-17 11:00:16October 17, 2020 | Wolverhampton Wanderers vs Derby County | 3 - 0 | U18 Premier League North | | Recap | 5 |
| 2020-10-17 11:00:30October 17, 2020 | Norwich City vs Crystal Palace | 2 - 3 | U18 Premier League South | Colney Training Centre | Recap | 5 |
| 2020-10-17 11:00:37October 17, 2020 | Reading vs Chelsea | 2 - 5 | U18 Premier League South | Reading Training Ground | Recap | 5 |
| 2020-10-17 11:00:47October 17, 2020 | Arsenal vs Brighton and Hove Albion | 0 - 5 | U18 Premier League South | Shenley Training Centre | Recap | 5 |
| 2020-10-17 11:00:54October 17, 2020 | Burnley vs Blackburn Rovers | 1 - 2 | U18 Premier League North | Leyland County Ground | Recap | 5 |
| 2020-10-17 11:30:48October 17, 2020 | West Bromwich Albion vs Fulham | 1 - 4 | U18 Premier League South | | Recap | 18 |
| 2020-10-17 12:00:03October 17, 2020 | Southampton vs Leicester City | 8 - 2 | U18 Premier League South | Staplewood Training Ground | Recap | 5 |
| 2020-10-17 12:00:19October 17, 2020 | Tottenham Hotspur vs Aston Villa | 0 - 2 | U18 Premier League South | | Recap | 5 |
| 2020-10-17 13:00:01October 17, 2020 | Middlesbrough vs Manchester City | 0 - 0 | U18 Premier League North | Rockliffe Park | Recap | 5 |
| 2020-10-17 13:00:06October 17, 2020 | Liverpool vs Sunderland | 3 - 2 | U18 Premier League North | Liverpool Academy | Recap | 5 |
| 2020-10-17 14:00:54October 17, 2020 | Stoke City vs Newcastle United | 1 - 1 | U18 Premier League North | Clayton Wood | Recap | 5 |
| 2020-10-23 12:15:55October 23, 2020 | Chelsea vs Norwich City | 4 - 3 | U18 Premier League South | Cobham Training Centre | Recap | 6 |
| 2020-10-24 11:00:17October 24, 2020 | Brighton and Hove Albion vs West Ham United | 2 - 3 | U18 Premier League South | The Amex Elite Football Performance Centre | Recap | 6 |
| 2020-10-24 11:00:40October 24, 2020 | Everton vs Liverpool | 0 - 4 | U18 Premier League North | Finch Farm | Recap | 6 |
| 2020-10-24 11:30:44October 24, 2020 | Tottenham Hotspur vs Reading | 4 - 4 | U18 Premier League South | | Recap | 6 |
| 2020-10-24 12:00:13October 24, 2020 | West Bromwich Albion vs Arsenal | 1 - 3 | U18 Premier League South | | Recap | 6 |
| 2020-10-24 12:00:33October 24, 2020 | Derby County vs Manchester United | 0 - 4 | U18 Premier League North | Derby County Football Academy | Recap | 6 |
| 2020-10-24 12:00:34October 24, 2020 | Blackburn Rovers vs Middlesbrough | 1 - 3 | U18 Premier League North | Brockhall | Recap | 6 |
| 2020-10-24 12:00:39October 24, 2020 | Aston Villa vs Fulham | 0 - 3 | U18 Premier League South | Bodymoor Heath Training Ground | Recap | 6 |
| 2020-10-24 12:00:41October 24, 2020 | Crystal Palace vs Leicester City | 1 - 0 | U18 Premier League South | Crystal Palace Training Ground | Recap | 6 |
| 2020-10-24 13:00:05October 24, 2020 | Sunderland vs Burnley | 1 - 3 | U18 Premier League North | Eppleton Colliery Welfare Ground | Recap | 6 |
| 2020-10-24 14:00:15October 24, 2020 | Wolverhampton Wanderers vs Leeds United | 2 - 0 | U18 Premier League North | | Recap | 19 |
| 2020-10-24 14:00:55October 24, 2020 | Newcastle United vs Manchester City | 0 - 1 | U18 Premier League North | Newcastle United Academy | Recap | 6 |
| 2020-10-31 11:00:19October 31, 2020 | Brighton and Hove Albion vs Leicester City | 7 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | Recap | 20 |
| 2020-10-31 11:00:20October 31, 2020 | Crystal Palace vs Reading | 1 - 0 | U18 Premier League South | Crystal Palace Training Ground | Recap | 7 |
| 2020-10-31 11:00:26October 31, 2020 | Burnley vs Leeds United | 3 - 2 | U18 Premier League North | Leyland County Ground | Recap | 7 |
| 2020-10-31 11:00:29October 31, 2020 | Arsenal vs Norwich City | 5 - 1 | U18 Premier League South | Shenley Training Centre | Recap | 7 |
| 2020-10-31 11:00:52October 31, 2020 | Southampton vs Fulham | 0 - 2 | U18 Premier League South | Staplewood Training Ground | Recap | 7 |
| 2020-10-31 12:30:32October 31, 2020 | Middlesbrough vs Everton | 2 - 0 | U18 Premier League North | Rockliffe Park | Recap | 7 |
| 2020-10-31 13:00:26October 31, 2020 | Liverpool vs Newcastle United | 4 - 1 | U18 Premier League North | Liverpool Academy | Recap | 7 |
| 2020-11-07 11:00:07November 7, 2020 | West Ham United vs Crystal Palace | 1 - 2 | U18 Premier League South | | Recap | 8 |
| 2020-11-07 11:00:14November 7, 2020 | Derby County vs Stoke City | 0 - 1 | U18 Premier League North | Derby County Football Academy | Recap | 8 |
| 2020-11-07 11:00:16November 7, 2020 | Manchester United vs Everton | 2 - 0 | U18 Premier League North | Aon Training Complex | Recap | 8 |
| 2020-11-07 11:00:23November 7, 2020 | Brighton and Hove Albion vs West Bromwich Albion | 2 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | Recap | 8 |
| 2020-11-07 11:30:02November 7, 2020 | Wolverhampton Wanderers vs Liverpool | 2 - 1 | U18 Premier League North | | Recap | 8 |
| 2020-11-07 11:30:12November 7, 2020 | Norwich City vs Tottenham Hotspur | 0 - 2 | U18 Premier League South | Colney Training Centre | Recap | 8 |
| 2020-11-07 12:00:28November 7, 2020 | Leeds United vs Manchester City | 0 - 2 | U18 Premier League North | Thorp Arch | Recap | 8 |
| 2020-11-07 12:00:44November 7, 2020 | Chelsea vs Leicester City | 8 - 1 | U18 Premier League South | Cobham Training Centre | Recap | 8 |
| 2020-11-07 13:00:08November 7, 2020 | Blackburn Rovers vs Sunderland | 2 - 2 | U18 Premier League North | Brockhall | Recap | 8 |
| 2020-11-07 13:00:09November 7, 2020 | Newcastle United vs Burnley | 2 - 1 | U18 Premier League North | Newcastle United Academy | Recap | 8 |
| 2020-11-07 13:00:16November 7, 2020 | Aston Villa vs Southampton | 3 - 3 | U18 Premier League South | Bodymoor Heath Training Ground | Recap | 8 |
| 2020-11-13 13:00:06November 13, 2020 | Middlesbrough vs Manchester United | 1 - 4 | U18 Premier League North | Rockliffe Park | Recap | 13 |
| 2020-11-21 11:00:10November 21, 2020 | Leicester City vs West Bromwich Albion | 1 - 3 | U18 Premier League South | Belvoir Drive Training Ground | Recap | 9 |
| 2020-11-21 11:00:19November 21, 2020 | Arsenal vs Fulham | 0 - 0 | U18 Premier League South | Shenley Training Centre | Recap | 9 |
| 2020-11-21 11:00:47November 21, 2020 | Stoke City vs Manchester United | 0 - 1 | U18 Premier League North | Clayton Wood | Recap | 9 |
| 2020-11-21 11:00:53November 21, 2020 | Reading vs West Ham United | 1 - 2 | U18 Premier League South | Reading Training Ground | Recap | 9 |
| 2020-11-21 11:30:20November 21, 2020 | Everton vs Derby County | 3 - 0 | U18 Premier League North | Finch Farm | Recap | 9 |
| 2020-11-21 11:30:55November 21, 2020 | Tottenham Hotspur vs Southampton | 7 - 0 | U18 Premier League South | | Recap | 9 |
| 2020-11-21 12:00:04November 21, 2020 | Liverpool vs Leeds United | 5 - 0 | U18 Premier League North | Liverpool Academy | Recap | 9 |
| 2020-11-21 12:00:09November 21, 2020 | Burnley vs Middlesbrough | 0 - 0 | U18 Premier League North | Leyland County Ground | Recap | 9 |
| 2020-11-21 12:00:54November 21, 2020 | Chelsea vs Aston Villa | 2 - 4 | U18 Premier League South | Cobham Training Centre | Recap | 9 |
| 2020-11-21 13:00:40November 21, 2020 | Norwich City vs Brighton and Hove Albion | 1 - 1 | U18 Premier League South | Colney Training Centre | Recap | 9 |
| 2020-11-21 14:00:06November 21, 2020 | Newcastle United vs Blackburn Rovers | 5 - 0 | U18 Premier League North | Newcastle United Academy | Recap | 9 |
| 2020-11-28 11:00:01November 28, 2020 | Aston Villa vs Crystal Palace | 2 - 1 | U18 Premier League South | Bodymoor Heath Training Ground | Recap | 10 |
| 2020-11-28 11:00:08November 28, 2020 | Stoke City vs Leeds United | 2 - 2 | U18 Premier League North | Clayton Wood | Recap | 10 |
| 2020-11-28 11:00:59November 28, 2020 | Southampton vs Norwich City | 1 - 2 | U18 Premier League South | Staplewood Training Ground | Recap | 10 |
| 2020-11-28 11:30:14November 28, 2020 | Tottenham Hotspur vs Leicester City | 1 - 1 | U18 Premier League South | | Recap | 10 |
| 2020-11-28 12:00:14November 28, 2020 | Reading vs Brighton and Hove Albion | 2 - 3 | U18 Premier League South | Reading Training Ground | Recap | 23 |
| 2020-11-28 12:00:22November 28, 2020 | West Bromwich Albion vs West Ham United | 2 - 2 | U18 Premier League South | | Recap | 10 |
| 2020-11-28 12:30:15November 28, 2020 | Manchester United vs Newcastle United | 4 - 1 | U18 Premier League North | Aon Training Complex | Recap | 10 |
| 2020-11-28 12:30:30November 28, 2020 | Derby County vs Blackburn Rovers | 5 - 1 | U18 Premier League North | Derby County Football Academy | Recap | 10 |
| 2020-11-28 13:00:11November 28, 2020 | Wolverhampton Wanderers vs Middlesbrough | 2 - 1 | U18 Premier League North | | Recap | 10 |
| 2020-11-28 14:00:14November 28, 2020 | Manchester City vs Sunderland | 5 - 0 | U18 Premier League North | Academy Stadium | Recap | 10 |
| 2020-12-01 18:30:40December 1, 2020 | Everton vs Leeds United | 3 - 0 | U18 Premier League North | Finch Farm | Recap | 5 |
| 2020-12-01 19:00:11December 1, 2020 | Liverpool vs Burnley | 4 - 1 | U18 Premier League North | Liverpool Academy | Recap | 10 |
| 2020-12-04 19:00:11December 4, 2020 | Stoke City vs Blackburn Rovers | 2 - 1 | U18 Premier League North | Clayton Wood | Recap | 7 |
| 2020-12-05 11:00:09December 5, 2020 | Reading vs Norwich City | 5 - 2 | U18 Premier League South | Reading Training Ground | Recap | 25 |
| 2020-12-05 11:00:12December 5, 2020 | Crystal Palace vs Tottenham Hotspur | 1 - 5 | U18 Premier League South | Crystal Palace Training Ground | Recap | 11 |
| 2020-12-05 11:30:01December 5, 2020 | Arsenal vs Leicester City | 2 - 1 | U18 Premier League South | Shenley Training Centre | Recap | 11 |
| 2020-12-05 11:30:08December 5, 2020 | Manchester United vs Liverpool | 4 - 3 | U18 Premier League North | Aon Training Complex | Recap | 1 |
| 2020-12-05 12:00:02December 5, 2020 | Everton vs Wolverhampton Wanderers | 2 - 3 | U18 Premier League North | Finch Farm | Recap | 12 |
| 2020-12-12 10:30:59December 12, 2020 | Fulham vs Chelsea | 2 - 1 | U18 Premier League South | Imber Court | Recap | 10 |
| 2020-12-12 11:00:35December 12, 2020 | Middlesbrough vs Liverpool | 1 - 4 | U18 Premier League North | Rockliffe Park | Recap | 11 |
| 2020-12-12 11:00:56December 12, 2020 | Sunderland vs Stoke City | 7 - 1 | U18 Premier League North | Eppleton Colliery Welfare Ground | Recap | 11 |
| 2020-12-12 11:30:39December 12, 2020 | Wolverhampton Wanderers vs Manchester United | 0 - 1 | U18 Premier League North | | Recap | 11 |
| 2020-12-12 12:00:41December 12, 2020 | West Ham United vs Norwich City | 0 - 3 | U18 Premier League South | | Recap | 11 |
| 2020-12-12 13:00:37December 12, 2020 | Burnley vs Manchester City | 13:00:371:00 pm | U18 Premier League North | Leyland County Ground | Recap | 11 |
| 2020-12-12 13:00:38December 12, 2020 | West Bromwich Albion vs Southampton | 3 - 1 | U18 Premier League South | | Recap | 11 |
| 2020-12-15 14:00:26December 15, 2020 | Manchester City vs Derby County | 7 - 0 | U18 Premier League North | Academy Stadium | Recap | 7 |
| 2020-12-16 13:00:16December 16, 2020 | Reading vs Fulham | 1 - 5 | U18 Premier League South | Reading Training Ground | Recap | 11 |
| 2020-12-17 11:30:04December 17, 2020 | Manchester United vs Leeds United | 4 - 0 | U18 Premier League North | Aon Training Complex | Recap | 12 |
| 2020-12-19 11:00:10December 19, 2020 | Blackburn Rovers vs Manchester City | 1 - 1 | U18 Premier League North | Brockhall | Recap | 12 |
| 2020-12-19 11:00:42December 19, 2020 | Everton vs Burnley | 0 - 1 | U18 Premier League North | Finch Farm | Recap | 17 |
| 2020-12-19 11:00:54December 19, 2020 | Crystal Palace vs Brighton and Hove Albion | 2 - 1 | U18 Premier League South | Crystal Palace Training Ground | Recap | 12 |
| 2020-12-19 11:30:51December 19, 2020 | Tottenham Hotspur vs West Bromwich Albion | 0 - 0 | U18 Premier League South | | Recap | 12 |
| 2020-12-19 12:00:38December 19, 2020 | Fulham vs Leicester City | 3 - 3 | U18 Premier League South | Belvoir Drive Training Ground | Recap | 25 |
| 2020-12-19 12:00:44December 19, 2020 | Derby County vs Liverpool | 1 - 3 | U18 Premier League North | Derby County Football Academy | Recap | 12 |
| 2021-01-09 14:00:22January 9, 2021 | Manchester City vs Stoke City | 14:00:222:00 pm | U18 Premier League North | Academy Stadium | Recap | 13 |
| 2021-01-16 11:00:10January 16, 2021 | Blackburn Rovers vs Everton | 11:00:1011:00 am | U18 Premier League North | Brockhall | Recap | 14 |
| 2021-01-16 11:00:45January 16, 2021 | Crystal Palace vs Fulham | 11:00:4511:00 am | U18 Premier League South | Crystal Palace Training Ground | Recap | 14 |
| 2021-01-16 13:00:15January 16, 2021 | West Bromwich Albion vs Norwich City | 13:00:151:00 pm | U18 Premier League South | | Recap | 14 |
| 2021-01-30 11:00:05January 30, 2021 | Middlesbrough vs Leeds United | 11:00:0511:00 am | U18 Premier League North | Rockliffe Park | Preview | 14 |
| 2021-02-06 11:00:06February 6, 2021 | Reading vs Southampton | 11:00:0611:00 am | U18 Premier League South | Reading Training Ground | Preview | 13 |
| 2021-02-06 11:00:10February 6, 2021 | Fulham vs Crystal Palace | 11:00:1011:00 am | U18 Premier League South | Imber Court | Preview | 1 |
| 2021-02-06 11:00:35February 6, 2021 | Sunderland vs Manchester United | 11:00:3511:00 am | U18 Premier League North | Eppleton Colliery Welfare Ground | Preview | 7 |
| 2021-02-06 12:00:34February 6, 2021 | West Ham United vs Aston Villa | 12:00:3412:00 pm | U18 Premier League South | | Preview | 7 |
| 2021-02-06 12:00:36February 6, 2021 | West Bromwich Albion vs Chelsea | 12:00:3612:00 pm | U18 Premier League South | | Preview | 7 |
| 2021-02-06 12:00:46February 6, 2021 | Leeds United vs Blackburn Rovers | 12:00:4612:00 pm | U18 Premier League North | Thorp Arch | Preview | 13 |
| 2021-02-06 12:30:24February 6, 2021 | Everton vs Newcastle United | 12:30:2412:30 pm | U18 Premier League North | Finch Farm | Preview | 11 |
| 2021-02-06 13:00:15February 6, 2021 | Stoke City vs Middlesbrough | 13:00:151:00 pm | U18 Premier League North | Clayton Wood | Preview | 12 |
| 2021-02-09 12:30:03February 9, 2021 | Leeds United vs Derby County | 12:30:0312:30 pm | U18 Premier League North | Thorp Arch | Preview | 11 |
| 2021-02-17 13:00:05February 17, 2021 | Sunderland vs Derby County | 13:00:051:00 pm | U18 Premier League North | Eppleton Colliery Welfare Ground | Preview | 14 |
| 2021-02-24 14:00:10February 24, 2021 | Wolverhampton Wanderers vs Manchester City | 14:00:102:00 pm | U18 Premier League North | | Preview | 14 |
| 2021-02-27 12:00:25February 27, 2021 | Leeds United vs Wolverhampton Wanderers | 12:00:2512:00 pm | U18 Premier League North | Thorp Arch | Preview | 6 |
| 2021-03-06 11:00:00March 6, 2021 | Liverpool vs Manchester United | 11:00:0011:00 am | U18 Premier League North | Liverpool Academy | Preview | 14 |
| 2021-03-06 11:00:08March 6, 2021 | Southampton vs West Ham United | 11:00:0811:00 am | U18 Premier League South | Staplewood Training Ground | Preview | 12 |
| 2021-03-06 11:00:09March 6, 2021 | Reading vs Arsenal | 11:00:0911:00 am | U18 Premier League South | Reading Training Ground | Preview | 8 |
| 2021-03-06 11:00:12March 6, 2021 | Wolverhampton Wanderers vs Newcastle United | 11:00:1211:00 am | U18 Premier League North | | Preview | 13 |
| 2021-03-06 11:00:13March 6, 2021 | Leicester City vs Aston Villa | 11:00:1311:00 am | U18 Premier League South | Belvoir Drive Training Ground | Preview | 14 |
| 2021-03-06 11:00:47March 6, 2021 | Chelsea vs Tottenham Hotspur | 11:00:4711:00 am | U18 Premier League South | Cobham Training Centre | Preview | 13 |
| 2021-03-06 11:00:56March 6, 2021 | West Bromwich Albion vs Crystal Palace | 11:00:5611:00 am | U18 Premier League South | | Preview | 13 |
| 2021-03-06 13:00:26March 6, 2021 | Sunderland vs Everton | 13:00:261:00 pm | U18 Premier League North | Eppleton Colliery Welfare Ground | Preview | 13 |
| 2021-03-09 12:30:30March 9, 2021 | Aston Villa vs Arsenal | 12:30:3012:30 pm | U18 Premier League South | Bodymoor Heath Training Ground | Preview | 13 |
| 2021-03-13 13:00:28March 13, 2021 | Leicester City vs Brighton and Hove Albion | 13:00:281:00 pm | U18 Premier League South | Belvoir Drive Training Ground | Preview | 7 |
| 2021-03-24 11:00:43March 24, 2021 | Tottenham Hotspur vs West Ham United | 11:00:4311:00 am | U18 Premier League South | | Preview | 14 |
| 2021-03-25 11:00:43March 25, 2021 | Sunderland vs Wolverhampton Wanderers | 11:00:4311:00 am | U18 Premier League North | Eppleton Colliery Welfare Ground | Preview | 9 |
| 2021-03-27 11:00:06March 27, 2021 | Burnley vs Stoke City | 11:00:0611:00 am | U18 Premier League North | Leyland County Ground | Preview | 14 |
| 2021-03-27 12:00:12March 27, 2021 | Fulham vs Norwich City | 12:00:1212:00 pm | U18 Premier League South | Imber Court | Preview | 13 |
| 2021-03-27 12:00:28March 27, 2021 | West Ham United vs Leicester City | 12:00:2812:00 pm | U18 Premier League South | | Preview | 13 |
| 2021-04-03 12:00:25April 3, 2021 | Newcastle United vs Sunderland | 12:00:2512:00 pm | U18 Premier League North | Newcastle United Academy | Preview | 12 |
| 2021-04-03 13:00:38April 3, 2021 | Aston Villa vs Brighton and Hove Albion | 13:00:38Postponed | U18 Premier League South | Bodymoor Heath Training Ground | Preview | 11 |
| 2021-04-06 11:30:44April 6, 2021 | Southampton vs Arsenal | 11:30:4411:30 am | U18 Premier League South | Staplewood Training Ground | Preview | 14 |
| 2021-04-17 12:00:19April 17, 2021 | Brighton and Hove Albion vs Reading | 12:00:1912:00 pm | U18 Premier League South | The Amex Elite Football Performance Centre | Preview | 10 |
| 2021-04-20 11:00:26April 20, 2021 | Arsenal vs Chelsea | 11:00:2611:00 am | U18 Premier League South | Shenley Training Centre | Preview | 12 |
| 2021-05-01 12:00:49May 1, 2021 | Leicester City vs Fulham | 12:00:4912:00 pm | U18 Premier League South | Belvoir Drive Training Ground | Preview | 12 |
| 2021-05-01 12:30:36May 1, 2021 | Norwich City vs Reading | 12:30:3612:30 pm | U18 Premier League South | Colney Training Centre | Preview | 12 |
| 2021-05-01 12:30:42May 1, 2021 | Norwich City vs Reading | 12:30:4212:30 pm | U18 Premier League South | Colney Training Centre | Preview | 12 |
| 2021-05-08 12:30:18May 8, 2021 | Burnley vs Derby County | 12:30:1812:30 pm | U18 Premier League North | Leyland County Ground | Preview | 13 |
| 2021-05-15 11:00:35May 15, 2021 | Chelsea vs Brighton and Hove Albion | 11:00:3511:00 am | U18 Premier League South | Cobham Training Centre | Preview | 14 |
