| 2021-08-14 11:00:06August 14, 2021 | Fulham vs Tottenham Hotspur | 4 - 2 | U18 Premier League South | Imber Court | 1 |
| 2021-08-14 11:00:11August 14, 2021 | Sunderland vs Wolverhampton Wanderers | 0 - 1 | U18 Premier League North | Eppleton Colliery Welfare Ground | 1 |
| 2021-08-14 11:00:12August 14, 2021 | Norwich City vs Southampton | 0 - 2 | U18 Premier League South | Colney Training Centre | 1 |
| 2021-08-14 11:00:12August 14, 2021 | West Ham United vs Reading | 3 - 1 | U18 Premier League South | | 1 |
| 2021-08-14 11:00:22August 14, 2021 | Liverpool vs Stoke City | 5 - 3 | U18 Premier League North | Liverpool Academy | 1 |
| 2021-08-14 12:00:03August 14, 2021 | Manchester City vs Manchester United | 3 - 0 | U18 Premier League North | Academy Stadium | 1 |
| 2021-08-14 12:00:19August 14, 2021 | Leicester City vs Crystal Palace | 1 - 3 | U18 Premier League South | Belvoir Drive Training Ground | 1 |
| 2021-08-14 12:00:27August 14, 2021 | Chelsea vs West Bromwich Albion | 5 - 2 | U18 Premier League South | Cobham Training Centre | 1 |
| 2021-08-14 12:00:51August 14, 2021 | Arsenal vs Aston Villa | 5 - 3 | U18 Premier League South | Shenley Training Centre | 1 |
| 2021-08-14 12:00:57August 14, 2021 | Leeds United vs Everton | 2 - 1 | U18 Premier League North | Thorp Arch | 1 |
| 2021-08-14 12:30:07August 14, 2021 | Middlesbrough vs Derby County | 0 - 3 | U18 Premier League North | Rockliffe Park | 1 |
| 2021-08-14 13:00:25August 14, 2021 | Birmingham City vs Brighton and Hove Albion | 2 - 3 | U18 Premier League South | Venue Trillion Trophy Training Centre | 1 |
| 2021-08-14 13:00:37August 14, 2021 | Newcastle United vs Burnley | 3 - 8 | U18 Premier League North | Newcastle United Academy | 1 |
| 2021-08-21 11:00:10August 21, 2021 | Brighton and Hove Albion vs Leicester City | 0 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | 2 |
| 2021-08-21 11:00:14August 21, 2021 | Aston Villa vs Norwich City | 10 - 0 | U18 Premier League South | Bodymoor Heath Training Ground | 2 |
| 2021-08-21 11:00:21August 21, 2021 | Crystal Palace vs West Ham United | 2 - 1 | U18 Premier League South | Crystal Palace Training Ground | 2 |
| 2021-08-21 11:00:30August 21, 2021 | Wolverhampton Wanderers vs Newcastle United | 2 - 2 | U18 Premier League North | | 2 |
| 2021-08-21 11:00:34August 21, 2021 | Tottenham Hotspur vs Chelsea | 2 - 7 | U18 Premier League South | | 2 |
| 2021-08-21 11:00:37August 21, 2021 | Reading vs Fulham | 0 - 1 | U18 Premier League South | Reading Training Ground | 2 |
| 2021-08-21 11:00:38August 21, 2021 | Everton vs Manchester City | 1 - 1 | U18 Premier League North | Finch Farm | 2 |
| 2021-08-21 11:30:21August 21, 2021 | Manchester United vs Liverpool | 0 - 5 | U18 Premier League North | Aon Training Complex | 2 |
| 2021-08-21 11:30:38August 21, 2021 | Southampton vs Birmingham City | 7 - 2 | U18 Premier League South | Staplewood Training Ground | 2 |
| 2021-08-21 12:00:34August 21, 2021 | West Bromwich Albion vs Arsenal | 1 - 3 | U18 Premier League South | | 2 |
| 2021-08-21 12:00:53August 21, 2021 | Burnley vs Middlesbrough | 2 - 2 | U18 Premier League North | Leyland County Ground | 2 |
| 2021-08-21 12:30:56August 21, 2021 | Derby County vs Blackburn Rovers | 1 - 6 | U18 Premier League North | Derby County Football Academy | 2 |
| 2021-08-21 13:00:56August 21, 2021 | Stoke City vs Sunderland | 3 - 0 | U18 Premier League North | Clayton Wood | 2 |
| 2021-08-21 13:00:58August 21, 2021 | Nottingham Forest vs Leeds United | 1 - 0 | U18 Premier League North | Nottingham Forest Academy | 2 |
| 2021-08-28 11:00:45August 28, 2021 | Newcastle United vs Stoke City | 3 - 0 | U18 Premier League North | Newcastle United Academy | 3 |
| 2021-08-28 11:00:56August 28, 2021 | West Ham United vs Southampton | 1 - 3 | U18 Premier League South | | 3 |
| 2021-08-28 11:30:18August 28, 2021 | Arsenal vs Brighton and Hove Albion | 2 - 2 | U18 Premier League South | Shenley Training Centre | 3 |
| 2021-08-28 11:30:27August 28, 2021 | Crystal Palace vs West Bromwich Albion | 3 - 2 | U18 Premier League South | Crystal Palace Training Ground | 3 |
| 2021-08-28 12:00:05August 28, 2021 | Fulham vs Aston Villa | 4 - 1 | U18 Premier League South | Imber Court | 3 |
| 2021-08-28 12:00:12August 28, 2021 | Blackburn Rovers vs Wolverhampton Wanderers | 5 - 2 | U18 Premier League North | Brockhall | 3 |
| 2021-08-28 12:00:29August 28, 2021 | Birmingham City vs Tottenham Hotspur | 3 - 2 | U18 Premier League South | Venue Trillion Trophy Training Centre | 3 |
| 2021-08-28 12:00:36August 28, 2021 | Leeds United vs Manchester United | 0 - 3 | U18 Premier League North | Thorp Arch | 3 |
| 2021-08-28 12:00:44August 28, 2021 | Leicester City vs Reading | 2 - 1 | U18 Premier League South | Belvoir Drive Training Ground | 3 |
| 2021-08-28 12:00:48August 28, 2021 | Norwich City vs Chelsea | 1 - 3 | U18 Premier League South | Colney Training Centre | 3 |
| 2021-08-28 12:30:54August 28, 2021 | Middlesbrough vs Everton | 4 - 1 | U18 Premier League North | Rockliffe Park | 3 |
| 2021-08-28 12:45:26August 28, 2021 | Sunderland vs Burnley | 2 - 0 | U18 Premier League North | Eppleton Colliery Welfare Ground | 3 |
| 2021-08-31 17:00:39August 31, 2021 | Blackburn Rovers vs Nottingham Forest | 3 - 1 | U18 Premier League North | Brockhall | 1 |
| 2021-09-11 11:00:33September 11, 2021 | Aston Villa vs Crystal Palace | 2 - 2 | U18 Premier League South | Bodymoor Heath Training Ground | 4 |
| 2021-09-11 11:00:43September 11, 2021 | Brighton and Hove Albion vs Norwich City | 3 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | 4 |
| 2021-09-11 11:30:09September 11, 2021 | Tottenham Hotspur vs Reading | 3 - 2 | U18 Premier League South | | 4 |
| 2021-09-11 11:30:19September 11, 2021 | Southampton vs Arsenal | 3 - 3 | U18 Premier League South | Staplewood Training Ground | 4 |
| 2021-09-11 12:00:18September 11, 2021 | West Ham United vs Leicester City | 3 - 1 | U18 Premier League South | | 4 |
| 2021-09-11 12:00:31September 11, 2021 | Chelsea vs Birmingham City | 3 - 0 | U18 Premier League South | Cobham Training Centre | 4 |
| 2021-09-11 12:30:03September 11, 2021 | Wolverhampton Wanderers vs Manchester City | 2 - 1 | U18 Premier League North | | 4 |
| 2021-09-11 12:30:33September 11, 2021 | Nottingham Forest vs Liverpool | 3 - 3 | U18 Premier League North | Nottingham Forest Academy | 4 |
| 2021-09-11 12:45:26September 11, 2021 | Everton vs Sunderland | 2 - 0 | U18 Premier League North | Finch Farm | 4 |
| 2021-09-11 13:00:45September 11, 2021 | Derby County vs Newcastle United | 0 - 3 | U18 Premier League North | Derby County Football Academy | 4 |
| 2021-09-11 13:00:59September 11, 2021 | Burnley vs Leeds United | 0 - 1 | U18 Premier League North | Leyland County Ground | 4 |
| 2021-09-11 13:30:30September 11, 2021 | West Bromwich Albion vs Fulham | 2 - 0 | U18 Premier League South | | 4 |
| 2021-09-21 19:00:56September 21, 2021 | Liverpool vs Derby County | 1 - 3 | U18 Premier League North | Liverpool Academy | 3 |
| 2021-09-25 11:00:33September 25, 2021 | Tottenham Hotspur vs West Ham United | 3 - 0 | U18 Premier League South | | 5 |
| 2021-09-25 11:00:34September 25, 2021 | Brighton and Hove Albion vs West Bromwich Albion | 7 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | 5 |
| 2021-09-25 11:00:48September 25, 2021 | Fulham vs Norwich City | 4 - 0 | U18 Premier League South | Imber Court | 5 |
| 2021-09-25 11:30:01September 25, 2021 | Everton vs Wolverhampton Wanderers | 2 - 1 | U18 Premier League North | Finch Farm | 5 |
| 2021-09-25 11:30:13September 25, 2021 | Manchester United vs Stoke City | 4 - 2 | U18 Premier League North | Aon Training Complex | 5 |
| 2021-09-25 12:00:02September 25, 2021 | Arsenal vs Birmingham City | 1 - 0 | U18 Premier League South | Shenley Training Centre | 5 |
| 2021-09-25 12:00:04September 25, 2021 | Leicester City vs Chelsea | 1 - 0 | U18 Premier League South | Belvoir Drive Training Ground | 5 |
| 2021-09-25 12:00:39September 25, 2021 | Reading vs Aston Villa | 5 - 2 | U18 Premier League South | Reading Training Ground | 5 |
| 2021-09-25 12:00:45September 25, 2021 | Leeds United vs Liverpool | 5 - 2 | U18 Premier League North | Thorp Arch | 5 |
| 2021-09-25 12:00:47September 25, 2021 | Manchester City vs Middlesbrough | 2 - 0 | U18 Premier League North | Academy Stadium | 5 |
| 2021-09-25 12:00:59September 25, 2021 | Crystal Palace vs Southampton | 1 - 0 | U18 Premier League South | Crystal Palace Training Ground | 5 |
| 2021-09-25 12:30:47September 25, 2021 | Blackburn Rovers vs Newcastle United | 2 - 1 | U18 Premier League North | Brockhall | 5 |
| 2021-09-25 13:00:04September 25, 2021 | Sunderland vs Derby County | 3 - 0 | U18 Premier League North | Eppleton Colliery Welfare Ground | 5 |
| 2021-09-25 13:00:38September 25, 2021 | Nottingham Forest vs Burnley | 0 - 3 | U18 Premier League North | Nottingham Forest Academy | 5 |
| 2021-10-02 11:00:08October 2, 2021 | Chelsea vs West Ham United | 1 - 2 | U18 Premier League South | Cobham Training Centre | 6 |
| 2021-10-02 11:00:23October 2, 2021 | Burnley vs Everton | 1 - 2 | U18 Premier League North | Leyland County Ground | 6 |
| 2021-10-02 11:00:43October 2, 2021 | Reading vs Crystal Palace | 3 - 3 | U18 Premier League South | Reading Training Ground | 6 |
| 2021-10-02 11:00:48October 2, 2021 | Southampton vs Leicester City | 0 - 3 | U18 Premier League South | Staplewood Training Ground | 6 |
| 2021-10-02 11:00:54October 2, 2021 | Stoke City vs Nottingham Forest | 0 - 0 | U18 Premier League North | Clayton Wood | 6 |
| 2021-10-02 11:30:32October 2, 2021 | Norwich City vs Arsenal | 0 - 3 | U18 Premier League South | Colney Training Centre | 6 |
| 2021-10-02 12:00:05October 2, 2021 | Middlesbrough vs Blackburn Rovers | 2 - 1 | U18 Premier League North | Rockliffe Park | 6 |
| 2021-10-02 12:00:48October 2, 2021 | West Bromwich Albion vs Tottenham Hotspur | 4 - 3 | U18 Premier League South | | 6 |
| 2021-10-02 12:00:51October 2, 2021 | Birmingham City vs Fulham | 0 - 3 | U18 Premier League South | Venue Trillion Trophy Training Centre | 6 |
| 2021-10-02 12:30:50October 2, 2021 | Derby County vs Manchester City | 1 - 6 | U18 Premier League North | Derby County Football Academy | 6 |
| 2021-10-02 12:45:42October 2, 2021 | Newcastle United vs Manchester United | 0 - 5 | U18 Premier League North | Newcastle United Academy | 6 |
| 2021-10-02 13:00:13October 2, 2021 | Wolverhampton Wanderers vs Leeds United | 2 - 1 | U18 Premier League North | | 6 |
| 2021-10-02 13:00:19October 2, 2021 | Liverpool vs Sunderland | 3 - 0 | U18 Premier League North | Liverpool Academy | 6 |
| 2021-10-02 13:00:40October 2, 2021 | Aston Villa vs Brighton and Hove Albion | 5 - 3 | U18 Premier League South | Bodymoor Heath Training Ground | 6 |
| 2021-10-07 12:30:45October 7, 2021 | Manchester United vs Middlesbrough | 3 - 3 | U18 Premier League North | Aon Training Complex | 4 |
| 2021-10-21 13:00:24October 21, 2021 | Sunderland vs Blackburn Rovers | 0 - 3 | U18 Premier League North | Eppleton Colliery Welfare Ground | 7 |
| 2021-10-21 13:00:31October 21, 2021 | Sunderland vs Blackburn Rovers | 0 - 3 | U18 Premier League North | Eppleton Colliery Welfare Ground | 7 |
| 2021-10-23 11:00:49October 23, 2021 | Fulham vs Chelsea | 4 - 4 | U18 Premier League South | Imber Court | 7 |
| 2021-10-23 11:30:51October 23, 2021 | Leicester City vs Arsenal | 2 - 1 | U18 Premier League South | Belvoir Drive Training Ground | 7 |
| 2021-10-23 12:00:04October 23, 2021 | Brighton and Hove Albion vs Reading | 3 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | 7 |
| 2021-10-23 12:00:06October 23, 2021 | West Ham United vs Aston Villa | 5 - 0 | U18 Premier League South | | 7 |
| 2021-10-23 12:00:11October 23, 2021 | Crystal Palace vs Birmingham City | 1 - 2 | U18 Premier League South | Crystal Palace Training Ground | 7 |
| 2021-10-23 12:00:49October 23, 2021 | Leeds United vs Stoke City | 0 - 2 | U18 Premier League North | Thorp Arch | 7 |
| 2021-10-23 12:30:16October 23, 2021 | Everton vs Newcastle United | 1 - 1 | U18 Premier League North | Finch Farm | 7 |
| 2021-10-23 13:30:15October 23, 2021 | Burnley vs Derby County | 1 - 1 | U18 Premier League North | Leyland County Ground | 7 |
| 2021-10-23 13:30:58October 23, 2021 | West Bromwich Albion vs Southampton | 1 - 5 | U18 Premier League South | | 7 |
| 2021-10-30 10:30:39October 30, 2021 | Chelsea vs Reading | 3 - 0 | U18 Premier League South | Cobham Training Centre | 8 |
| 2021-10-30 11:00:07October 30, 2021 | Arsenal vs Crystal Palace | 2 - 3 | U18 Premier League South | Shenley Training Centre | 8 |
| 2021-10-30 11:00:17October 30, 2021 | Southampton vs Brighton and Hove Albion | 3 - 2 | U18 Premier League South | Staplewood Training Ground | 8 |
| 2021-10-30 11:00:41October 30, 2021 | Norwich City vs West Bromwich Albion | 0 - 1 | U18 Premier League South | Colney Training Centre | 8 |
| 2021-10-30 11:00:42October 30, 2021 | Liverpool vs Everton | 4 - 0 | U18 Premier League North | Liverpool Academy | 8 |
| 2021-10-30 11:00:58October 30, 2021 | Newcastle United vs Manchester City | 2 - 2 | U18 Premier League North | Newcastle United Academy | 8 |
| 2021-10-30 12:00:00October 30, 2021 | Derby County vs Manchester United | 2 - 2 | U18 Premier League North | Derby County Football Academy | 8 |
| 2021-10-30 12:00:07October 30, 2021 | Aston Villa vs Tottenham Hotspur | 1 - 3 | U18 Premier League South | Bodymoor Heath Training Ground | 8 |
| 2021-10-30 12:00:40October 30, 2021 | Leicester City vs Fulham | 1 - 0 | U18 Premier League South | Belvoir Drive Training Ground | 8 |
| 2021-10-30 12:00:54October 30, 2021 | Blackburn Rovers vs Leeds United | 1 - 1 | U18 Premier League North | Brockhall | 8 |
| 2021-10-30 12:30:21October 30, 2021 | Sunderland vs Nottingham Forest | 1 - 0 | U18 Premier League North | Eppleton Colliery Welfare Ground | 8 |
| 2021-10-30 12:30:56October 30, 2021 | Wolverhampton Wanderers vs Burnley | 3 - 0 | U18 Premier League North | | 8 |
| 2021-10-30 13:00:23October 30, 2021 | Middlesbrough vs Stoke City | 1 - 1 | U18 Premier League North | Rockliffe Park | 8 |
| 2021-11-05 19:00:51November 5, 2021 | Stoke City vs Burnley | 1 - 3 | U18 Premier League North | Clayton Wood | 9 |
| 2021-11-06 11:00:02November 6, 2021 | Wolverhampton Wanderers vs Derby County | 2 - 2 | U18 Premier League North | | 9 |
| 2021-11-06 11:00:07November 6, 2021 | Everton vs Blackburn Rovers | 1 - 1 | U18 Premier League North | Finch Farm | 9 |
| 2021-11-06 11:00:11November 6, 2021 | Norwich City vs Birmingham City | 3 - 1 | U18 Premier League South | Colney Training Centre | 9 |
| 2021-11-06 11:00:14November 6, 2021 | Crystal Palace vs Chelsea | 3 - 4 | U18 Premier League South | Crystal Palace Training Ground | 9 |
| 2021-11-06 11:00:38November 6, 2021 | Reading vs Arsenal | 0 - 1 | U18 Premier League South | Reading Training Ground | 9 |
| 2021-11-06 11:00:47November 6, 2021 | West Ham United vs Fulham | 0 - 0 | U18 Premier League South | | 9 |
| 2021-11-06 11:30:24November 6, 2021 | Tottenham Hotspur vs Brighton and Hove Albion | 2 - 1 | U18 Premier League South | | 9 |
| 2021-11-06 12:00:27November 6, 2021 | Leeds United vs Newcastle United | 5 - 1 | U18 Premier League North | Thorp Arch | 9 |
| 2021-11-06 12:30:17November 6, 2021 | Liverpool vs Middlesbrough | 3 - 4 | U18 Premier League North | Liverpool Academy | 9 |
| 2021-11-06 12:30:45November 6, 2021 | Nottingham Forest vs Manchester United | 0 - 2 | U18 Premier League North | Nottingham Forest Academy | 26 |
| 2021-11-06 13:00:41November 6, 2021 | Southampton vs Aston Villa | 6 - 3 | U18 Premier League South | Staplewood Training Ground | 9 |
| 2021-11-06 13:30:18November 6, 2021 | West Bromwich Albion vs Leicester City | 3 - 3 | U18 Premier League South | | 9 |
| 2021-11-11 13:00:51November 11, 2021 | Manchester City vs Sunderland | 2 - 1 | U18 Premier League North | Academy Stadium | 9 |
| 2021-11-20 11:00:06November 20, 2021 | Burnley vs Manchester United | 2 - 2 | U18 Premier League North | Leyland County Ground | 10 |
| 2021-11-20 11:00:10November 20, 2021 | Derby County vs Stoke City | 2 - 1 | U18 Premier League North | Derby County Football Academy | 10 |
| 2021-11-20 11:00:15November 20, 2021 | Aston Villa vs West Bromwich Albion | 1 - 0 | U18 Premier League South | Bodymoor Heath Training Ground | 10 |
| 2021-11-20 11:00:16November 20, 2021 | Brighton and Hove Albion vs Chelsea | 1 - 6 | U18 Premier League South | The Amex Elite Football Performance Centre | 10 |
| 2021-11-20 11:00:32November 20, 2021 | Newcastle United vs Sunderland | 0 - 1 | U18 Premier League North | Newcastle United Academy | 10 |
| 2021-11-20 11:00:43November 20, 2021 | Fulham vs Crystal Palace | 1 - 1 | U18 Premier League South | Imber Court | 10 |
| 2021-11-20 11:00:46November 20, 2021 | Blackburn Rovers vs Liverpool | 3 - 1 | U18 Premier League North | Brockhall | 10 |
| 2021-11-20 11:00:52November 20, 2021 | Arsenal vs West Ham United | 2 - 2 | U18 Premier League South | Shenley Training Centre | 10 |
| 2021-11-20 11:30:04November 20, 2021 | Tottenham Hotspur vs Southampton | 0 - 3 | U18 Premier League South | | 10 |
| 2021-11-20 12:00:09November 20, 2021 | Birmingham City vs Reading | 1 - 3 | U18 Premier League South | Venue Trillion Trophy Training Centre | 10 |
| 2021-11-20 12:00:11November 20, 2021 | Manchester City vs Leeds United | 3 - 3 | U18 Premier League North | Academy Stadium | 10 |
| 2021-11-20 12:30:56November 20, 2021 | Leicester City vs Norwich City | 7 - 0 | U18 Premier League South | Belvoir Drive Training Ground | 10 |
| 2021-12-01 13:00:12December 1, 2021 | Manchester City vs Nottingham Forest | 4 - 1 | U18 Premier League North | Academy Stadium | 3 |
| 2021-12-04 11:00:09December 4, 2021 | West Bromwich Albion vs Birmingham City | 1 - 1 | U18 Premier League South | | 11 |
| 2021-12-04 11:00:14December 4, 2021 | Southampton vs Fulham | 2 - 0 | U18 Premier League South | Staplewood Training Ground | 11 |
| 2021-12-04 11:00:27December 4, 2021 | Everton vs Manchester United | 3 - 0 | U18 Premier League North | Finch Farm | 11 |
| 2021-12-04 11:00:30December 4, 2021 | Reading vs Norwich City | 2 - 0 | U18 Premier League South | Reading Training Ground | 11 |
| 2021-12-04 11:00:34December 4, 2021 | Sunderland vs Middlesbrough | 3 - 4 | U18 Premier League North | Eppleton Colliery Welfare Ground | 11 |
| 2021-12-04 11:00:45December 4, 2021 | Crystal Palace vs Tottenham Hotspur | 3 - 0 | U18 Premier League South | Crystal Palace Training Ground | 11 |
| 2021-12-04 11:00:49December 4, 2021 | Chelsea vs Arsenal | 4 - 1 | U18 Premier League South | Cobham Training Centre | 11 |
| 2021-12-04 12:00:03December 4, 2021 | Wolverhampton Wanderers vs Nottingham Forest | 0 - 3 | U18 Premier League North | | 11 |
| 2021-12-04 12:00:43December 4, 2021 | Stoke City vs Manchester City | 2 - 0 | U18 Premier League North | Clayton Wood | 11 |
| 2021-12-04 13:00:53December 4, 2021 | Liverpool vs Newcastle United | 3 - 1 | U18 Premier League North | Liverpool Academy | 11 |
| 2021-12-11 11:30:34December 11, 2021 | Tottenham Hotspur vs Leicester City | 0 - 3 | U18 Premier League South | | 12 |
| 2021-12-17 14:00:42December 17, 2021 | Norwich City vs West Ham United | 0 - 2 | U18 Premier League South | Colney Training Centre | 12 |
| 2021-12-18 11:00:11December 18, 2021 | Aston Villa vs Birmingham City | 1 - 1 | U18 Premier League South | Bodymoor Heath Training Ground | 26 |
| 2021-12-18 11:00:36December 18, 2021 | Burnley vs Liverpool | 0 - 5 | U18 Premier League North | Leyland County Ground | 12 |
| 2021-12-18 11:00:47December 18, 2021 | Stoke City vs Wolverhampton Wanderers | 0 - 4 | U18 Premier League North | Clayton Wood | 12 |
| 2021-12-18 11:00:56December 18, 2021 | Middlesbrough vs Leeds United | 2 - 2 | U18 Premier League North | Rockliffe Park | 12 |
| 2021-12-18 11:00:58December 18, 2021 | Fulham vs Arsenal | 1 - 1 | U18 Premier League South | Imber Court | 12 |
| 2022-01-08 11:00:28January 8, 2022 | Derby County vs Nottingham Forest | 3 - 2 | U18 Premier League North | Derby County Football Academy | 13 |
| 2022-01-08 11:00:33January 8, 2022 | Everton vs Stoke City | 2 - 2 | U18 Premier League North | Finch Farm | 13 |
| 2022-01-08 11:00:58January 8, 2022 | Arsenal vs Tottenham Hotspur | 3 - 2 | U18 Premier League South | Shenley Training Centre | 13 |
| 2022-01-08 12:00:24January 8, 2022 | Sunderland vs Leeds United | 7 - 5 | U18 Premier League North | Eppleton Colliery Welfare Ground | 13 |
| 2022-01-08 12:00:45January 8, 2022 | Leicester City vs Birmingham City | 2 - 1 | U18 Premier League South | Belvoir Drive Training Ground | 13 |
| 2022-01-08 12:30:22January 8, 2022 | Crystal Palace vs Norwich City | 0 - 0 | U18 Premier League South | Crystal Palace Training Ground | 13 |
| 2022-01-08 12:30:38January 8, 2022 | West Bromwich Albion vs West Ham United | 2 - 5 | U18 Premier League South | | 13 |
| 2022-01-11 12:00:30January 11, 2022 | Manchester City vs Burnley | 2 - 1 | U18 Premier League North | Academy Stadium | 17 |
| 2022-01-11 12:00:40January 11, 2022 | Manchester City vs Burnley | 2 - 1 | U18 Premier League North | Academy Stadium | 17 |
| 2022-01-15 11:00:16January 15, 2022 | West Ham United vs Arsenal | 3 - 0 | U18 Premier League South | | 14 |
| 2022-01-15 11:00:24January 15, 2022 | Chelsea vs Brighton and Hove Albion | 1 - 1 | U18 Premier League South | Cobham Training Centre | 14 |
| 2022-01-15 11:00:29January 15, 2022 | Liverpool vs Manchester City | 0 - 1 | U18 Premier League North | Liverpool Academy | 14 |
| 2022-01-15 11:30:23January 15, 2022 | Southampton vs Tottenham Hotspur | 1 - 2 | U18 Premier League South | Staplewood Training Ground | 14 |
| 2022-01-15 12:00:52January 15, 2022 | Leeds United vs Blackburn Rovers | 0 - 5 | U18 Premier League North | Thorp Arch | 14 |
| 2022-01-15 12:30:51January 15, 2022 | Nottingham Forest vs Sunderland | 1 - 1 | U18 Premier League North | Nottingham Forest Academy | 14 |
| 2022-01-15 15:00:52January 15, 2022 | Stoke City vs Derby County | 3 - 0 | U18 Premier League North | Clayton Wood | 14 |
| 2022-01-22 11:00:12January 22, 2022 | Manchester United vs Everton | 4 - 2 | U18 Premier League North | Aon Training Complex | 15 |
| 2022-01-22 11:00:26January 22, 2022 | Fulham vs West Ham United | 1 - 3 | U18 Premier League South | Imber Court | 15 |
| 2022-01-22 11:00:36January 22, 2022 | Brighton and Hove Albion vs Southampton | 3 - 4 | U18 Premier League South | The Amex Elite Football Performance Centre | 15 |
| 2022-01-22 11:00:52January 22, 2022 | Sunderland vs Newcastle United | 3 - 2 | U18 Premier League North | Eppleton Colliery Welfare Ground | 15 |
| 2022-01-22 12:00:08January 22, 2022 | Derby County vs Leeds United | 5 - 1 | U18 Premier League North | Derby County Football Academy | 15 |
| 2022-01-22 12:00:15January 22, 2022 | Manchester City vs Stoke City | 5 - 0 | U18 Premier League North | Academy Stadium | 15 |
| 2022-01-22 12:00:25January 22, 2022 | Arsenal vs Chelsea | 4 - 0 | U18 Premier League South | Shenley Training Centre | 15 |
| 2022-01-22 12:00:25January 22, 2022 | Birmingham City vs Crystal Palace | 0 - 4 | U18 Premier League South | Venue Trillion Trophy Training Centre | 15 |
| 2022-01-22 12:30:45January 22, 2022 | Norwich City vs Reading | 1 - 4 | U18 Premier League South | Colney Training Centre | 15 |
| 2022-01-22 13:00:41January 22, 2022 | Burnley vs Blackburn Rovers | 1 - 1 | U18 Premier League North | Leyland County Ground | 15 |
| 2022-01-22 13:00:55January 22, 2022 | Middlesbrough vs Liverpool | 2 - 6 | U18 Premier League North | Rockliffe Park | 15 |
| 2022-01-25 13:00:02January 25, 2022 | Aston Villa vs Chelsea | 1 - 4 | U18 Premier League South | Bodymoor Heath Training Ground | 13 |
| 2022-01-25 13:00:25January 25, 2022 | Birmingham City vs West Ham United | 1 - 3 | U18 Premier League South | Venue Trillion Trophy Training Centre | 8 |
| 2022-01-27 13:00:47January 27, 2022 | Wolverhampton Wanderers vs Middlesbrough | 2 - 0 | U18 Premier League North | | 14 |
| 2022-01-29 12:00:50January 29, 2022 | Derby County vs Everton | 1 - 0 | U18 Premier League North | Derby County Football Academy | 12 |
| 2022-02-01 12:00:38February 1, 2022 | Manchester City vs Blackburn Rovers | 4 - 0 | U18 Premier League North | Academy Stadium | 12 |
| 2022-02-04 11:00:32February 4, 2022 | Aston Villa vs Southampton | 0 - 5 | U18 Premier League South | Bodymoor Heath Training Ground | 16 |
| 2022-02-05 11:00:02February 5, 2022 | Tottenham Hotspur vs Crystal Palace | 2 - 4 | U18 Premier League South | | 16 |
| 2022-02-05 11:00:18February 5, 2022 | West Bromwich Albion vs Norwich City | 2 - 1 | U18 Premier League South | | 16 |
| 2022-02-05 11:00:27February 5, 2022 | Liverpool vs Burnley | 4 - 1 | U18 Premier League North | Liverpool Academy | 16 |
| 2022-02-05 11:00:35February 5, 2022 | Chelsea vs Fulham | 0 - 2 | U18 Premier League South | Cobham Training Centre | 16 |
| 2022-02-05 11:30:27February 5, 2022 | Arsenal vs Leicester City | 1 - 1 | U18 Premier League South | Shenley Training Centre | 16 |
| 2022-02-05 12:00:06February 5, 2022 | Reading vs Brighton and Hove Albion | 0 - 2 | U18 Premier League South | Reading Training Ground | 16 |
| 2022-02-05 12:00:43February 5, 2022 | West Ham United vs Birmingham City | 5 - 0 | U18 Premier League South | | 16 |
| 2022-02-05 13:00:04February 5, 2022 | Blackburn Rovers vs Sunderland | 1 - 3 | U18 Premier League North | Brockhall | 16 |
| 2022-02-05 13:00:17February 5, 2022 | Stoke City vs Middlesbrough | 1 - 2 | U18 Premier League North | Clayton Wood | 16 |
| 2022-02-05 13:00:41February 5, 2022 | Leeds United vs Manchester City | 3 - 8 | U18 Premier League North | Thorp Arch | 16 |
| 2022-02-05 14:00:29February 5, 2022 | Newcastle United vs Nottingham Forest | 0 - 1 | U18 Premier League North | Newcastle United Academy | 16 |
| 2022-02-12 12:00:15February 12, 2022 | Leeds United vs Derby County | 7 - 0 | U18 Premier League North | Thorp Arch | 11 |
| 2022-02-12 12:00:28February 12, 2022 | Nottingham Forest vs Everton | 0 - 1 | U18 Premier League North | Nottingham Forest Academy | 10 |
| 2022-02-15 13:00:23February 15, 2022 | Everton vs Derby County | 2 - 0 | U18 Premier League North | Finch Farm | 16 |
| 2022-02-19 11:00:13February 19, 2022 | Crystal Palace vs Arsenal | 5 - 0 | U18 Premier League South | Crystal Palace Training Ground | 17 |
| 2022-02-19 11:00:42February 19, 2022 | Fulham vs Brighton and Hove Albion | 5 - 1 | U18 Premier League South | Imber Court | 17 |
| 2022-02-19 11:00:44February 19, 2022 | Nottingham Forest vs Derby County | 0 - 1 | U18 Premier League North | Nottingham Forest Academy | 17 |
| 2022-02-19 11:00:47February 19, 2022 | Birmingham City vs Norwich City | 5 - 1 | U18 Premier League South | Venue Trillion Trophy Training Centre | 17 |
| 2022-02-19 12:00:00February 19, 2022 | Leicester City vs Tottenham Hotspur | 4 - 1 | U18 Premier League South | Belvoir Drive Training Ground | 17 |
| 2022-02-19 12:00:26February 19, 2022 | Aston Villa vs West Ham United | 0 - 0 | U18 Premier League South | Bodymoor Heath Training Ground | 17 |
| 2022-02-19 12:30:48February 19, 2022 | Liverpool vs Wolverhampton Wanderers | 2 - 1 | U18 Premier League North | Liverpool Academy | 17 |
| 2022-02-19 13:00:47February 19, 2022 | Southampton vs West Bromwich Albion | 2 - 1 | U18 Premier League South | Staplewood Training Ground | 17 |
| 2022-02-22 12:00:37February 22, 2022 | Newcastle United vs Middlesbrough | 0 - 1 | U18 Premier League North | Newcastle United Academy | 13 |
| 2022-02-26 11:00:00February 26, 2022 | Norwich City vs Crystal Palace | 0 - 1 | U18 Premier League South | Colney Training Centre | 18 |
| 2022-02-26 11:00:26February 26, 2022 | Blackburn Rovers vs Manchester City | 1 - 2 | U18 Premier League North | Brockhall | 18 |
| 2022-02-26 11:00:26February 26, 2022 | Everton vs Liverpool | 1 - 3 | U18 Premier League North | Finch Farm | 18 |
| 2022-02-26 11:00:39February 26, 2022 | Burnley vs Stoke City | 3 - 1 | U18 Premier League North | Leyland County Ground | 18 |
| 2022-02-26 11:00:45February 26, 2022 | Fulham vs Southampton | 2 - 3 | U18 Premier League South | Imber Court | 18 |
| 2022-02-26 11:00:47February 26, 2022 | Arsenal vs Reading | 4 - 2 | U18 Premier League South | Shenley Training Centre | 18 |
| 2022-02-26 12:00:09February 26, 2022 | Chelsea vs Aston Villa | 3 - 1 | U18 Premier League South | Cobham Training Centre | 18 |
| 2022-02-26 12:00:24February 26, 2022 | Newcastle United vs Leeds United | 1 - 1 | U18 Premier League North | Newcastle United Academy | 18 |
| 2022-02-26 12:00:25February 26, 2022 | West Ham United vs West Bromwich Albion | 6 - 0 | U18 Premier League South | | 18 |
| 2022-02-26 12:30:43February 26, 2022 | Middlesbrough vs Nottingham Forest | 0 - 2 | U18 Premier League North | Rockliffe Park | 18 |
| 2022-03-01 13:00:06March 1, 2022 | Birmingham City vs Leicester City | 1 - 1 | U18 Premier League South | Venue Trillion Trophy Training Centre | 18 |
| 2022-03-05 11:00:17March 5, 2022 | Reading vs West Ham United | 0 - 6 | U18 Premier League South | Reading Training Ground | 19 |
| 2022-03-05 11:00:32March 5, 2022 | Tottenham Hotspur vs Fulham | 0 - 1 | U18 Premier League South | | 19 |
| 2022-03-05 11:00:37March 5, 2022 | Manchester United vs Manchester City | 1 - 5 | U18 Premier League North | Aon Training Complex | 19 |
| 2022-03-05 11:00:41March 5, 2022 | Southampton vs Norwich City | 5 - 0 | U18 Premier League South | Staplewood Training Ground | 19 |
| 2022-03-05 11:30:07March 5, 2022 | Stoke City vs Liverpool | 0 - 2 | U18 Premier League North | Clayton Wood | 19 |
| 2022-03-05 12:00:20March 5, 2022 | Everton vs Leeds United | 1 - 4 | U18 Premier League North | Finch Farm | 19 |
| 2022-03-05 12:00:39March 5, 2022 | Crystal Palace vs Leicester City | 2 - 1 | U18 Premier League South | Crystal Palace Training Ground | 19 |
| 2022-03-05 12:00:49March 5, 2022 | Aston Villa vs Arsenal | 2 - 3 | U18 Premier League South | Bodymoor Heath Training Ground | 19 |
| 2022-03-05 12:00:56March 5, 2022 | West Bromwich Albion vs Chelsea | 0 - 2 | U18 Premier League South | | 19 |
| 2022-03-05 12:30:59March 5, 2022 | Derby County vs Middlesbrough | 1 - 1 | U18 Premier League North | Derby County Football Academy | 19 |
| 2022-03-05 13:00:19March 5, 2022 | Burnley vs Newcastle United | 2 - 0 | U18 Premier League North | Leyland County Ground | 19 |
| 2022-03-05 13:00:38March 5, 2022 | Brighton and Hove Albion vs Birmingham City | 3 - 1 | U18 Premier League South | The Amex Elite Football Performance Centre | 19 |
| 2022-03-08 11:00:15March 8, 2022 | Aston Villa vs Leicester City | 1 - 1 | U18 Premier League South | Bodymoor Heath Training Ground | 11 |
| 2022-03-08 13:00:36March 8, 2022 | Brighton and Hove Albion vs Fulham | 2 - 3 | U18 Premier League South | The Amex Elite Football Performance Centre | 13 |
| 2022-03-15 12:00:59March 15, 2022 | West Ham United vs Brighton and Hove Albion | 3 - 2 | U18 Premier League South | | 11 |
| 2022-03-16 12:00:15March 16, 2022 | Reading vs Chelsea | 2 - 2 | U18 Premier League South | Reading Training Ground | 17 |
| 2022-03-22 13:00:56March 22, 2022 | Reading vs Birmingham City | 3 - 1 | U18 Premier League South | Reading Training Ground | 14 |
| 2022-03-24 13:00:11March 24, 2022 | Sunderland vs Manchester United | 0 - 1 | U18 Premier League North | Eppleton Colliery Welfare Ground | 18 |
| 2022-03-25 12:30:07March 25, 2022 | Norwich City vs Leicester City | 0 - 3 | U18 Premier League South | Colney Training Centre | 14 |
| 2022-03-26 12:00:18March 26, 2022 | Nottingham Forest vs Middlesbrough | 3 - 0 | U18 Premier League North | Nottingham Forest Academy | 7 |
| 2022-03-26 12:00:42March 26, 2022 | Tottenham Hotspur vs Aston Villa | 0 - 2 | U18 Premier League South | | 15 |
| 2022-03-26 12:30:43March 26, 2022 | Newcastle United vs Everton | 0 - 0 | U18 Premier League North | Newcastle United Academy | 14 |
| 2022-03-29 12:00:11March 29, 2022 | Nottingham Forest vs Wolverhampton Wanderers | 1 - 1 | U18 Premier League North | Nottingham Forest Academy | 15 |
| 2022-03-29 13:00:11March 29, 2022 | Blackburn Rovers vs Manchester United | 4 - 1 | U18 Premier League North | Brockhall | 13 |
| 2022-04-05 13:00:34April 5, 2022 | Manchester United vs Sunderland | 1 - 1 | U18 Premier League North | Aon Training Complex | 12 |
| 2022-04-12 11:00:04April 12, 2022 | Leicester City vs West Bromwich Albion | 1 - 5 | U18 Premier League South | Belvoir Drive Training Ground | 15 |
| 2022-04-12 13:00:24April 12, 2022 | Blackburn Rovers vs Burnley | 1 - 2 | U18 Premier League North | Brockhall | 11 |
| 2022-04-12 13:30:43April 12, 2022 | Nottingham Forest vs Newcastle United | 1 - 0 | U18 Premier League North | Nottingham Forest Academy | 12 |
| 2022-04-12 19:00:45April 12, 2022 | Manchester United vs Wolverhampton Wanderers | 2 - 0 | U18 Premier League North | Aon Training Complex | 7 |
| 2022-04-14 12:00:56April 14, 2022 | Manchester City vs Liverpool | 3 - 1 | U18 Premier League North | Academy Stadium | 7 |
| 2022-04-15 12:00:54April 15, 2022 | Tottenham Hotspur vs Norwich City | 2 - 1 | U18 Premier League South | | 7 |
| 2022-04-16 11:00:22April 16, 2022 | Middlesbrough vs Wolverhampton Wanderers | 1 - 0 | U18 Premier League North | Rockliffe Park | 10 |
| 2022-04-16 11:00:51April 16, 2022 | West Bromwich Albion vs Aston Villa | 2 - 0 | U18 Premier League South | | 14 |
| 2022-04-19 11:00:01April 19, 2022 | Middlesbrough vs Newcastle United | 2 - 1 | U18 Premier League North | Rockliffe Park | 17 |
| 2022-04-19 13:00:13April 19, 2022 | Leeds United vs Sunderland | 2 - 2 | U18 Premier League North | Thorp Arch | 17 |
| 2022-04-19 13:00:29April 19, 2022 | Nottingham Forest vs Blackburn Rovers | 3 - 2 | U18 Premier League North | Nottingham Forest Academy | 19 |
| 2022-04-19 14:00:20April 19, 2022 | Wolverhampton Wanderers vs Liverpool | 1 - 5 | U18 Premier League North | | 13 |
| 2022-04-19 19:00:06April 19, 2022 | Manchester United vs Burnley | 19:00:067:00 pm | U18 Premier League North | Aon Training Complex | 14 |
| 2022-04-26 15:00:04April 26, 2022 | Stoke City vs Everton | 15:00:043:00 pm | U18 Premier League North | Clayton Wood | 17 |
| 2022-04-26 19:00:59April 26, 2022 | Manchester United vs Blackburn Rovers | 19:00:597:00 pm | U18 Premier League North | Aon Training Complex | 17 |
| 2022-04-27 18:30:34April 27, 2022 | Wolverhampton Wanderers vs Manchester United | 18:30:346:30 pm | U18 Premier League North | | 16 |
| 2022-05-03 12:00:17May 3, 2022 | Burnley vs Manchester City | 12:00:1712:00 pm | U18 Premier League North | Leyland County Ground | 13 |
| 2022-05-03 12:30:00May 3, 2022 | Brighton and Hove Albion vs Tottenham Hotspur | 12:30:0012:30 pm | U18 Premier League South | The Amex Elite Football Performance Centre | 18 |
| 2022-05-03 13:00:19May 3, 2022 | Derby County vs Wolverhampton Wanderers | 13:00:191:00 pm | U18 Premier League North | Derby County Football Academy | 18 |
| 2022-05-04 11:00:41May 4, 2022 | Southampton vs Reading | 11:00:4111:00 am | U18 Premier League South | Staplewood Training Ground | 13 |
| 2022-05-07 12:30:19May 7, 2022 | Manchester United vs Nottingham Forest | 12:30:1912:30 pm | U18 Premier League North | Aon Training Complex | 9 |
| 2022-05-10 13:00:40May 10, 2022 | Wolverhampton Wanderers vs Sunderland | 13:00:401:00 pm | U18 Premier League North | | 19 |
| 2022-05-14 11:00:35May 14, 2022 | Crystal Palace vs Fulham | 11:00:3511:00 am | U18 Premier League South | Crystal Palace Training Ground | 14 |
